precision medicine is highly personalized medicine that uses innovations in genomic testing to diagnose rare diseases. learn more about precision medicine treatment.
precision medicine (pm) and population health may seem contradictory concepts, with pm focusing on individual characteristics of each patient and population health focusing on outcomes of a large group of people. the bridge between the two is precision health (ph), a broader holistic approach, integrating individual and population-specific data to provide positive outcomes for a large group of people. when last year efpia approached the efpia oncology platform (eop) for a joint project on the potential of precision medicine and precision health to address common diseases at population level, i thought “interesting, bold”. i liked the chance to take pm out of the ivory tower, debunk the myth that pm is a “solution for a few”. pm brings value for individual patients, but its greatest impact is at the population level: this is the outcome of the research done by efpia, with charles river associates available in the recently published report adoption of precision health and precision medicine approaches in addressing population health needs in europe. from myth to reality: by focusing on individual information and genomics and channeling the right approach to the right patient at the right time we can reach benefits at population level. one of the examples of the report relates to covid-19, not a disease of a few, but a pandemic: the use of genomic sequencing enabled more effective disease surveillance and the development of vaccines targeting specific mutations in different strains of the virus. this approach proved how pm can bring significant value in prevention at population level. the report highlights that personalised care approaches emerge as the way to gain efficiency in the system and that we need collectively to intensify the effort for policies which can facilitate pm adoption in europe. in pm, oncology is the tip of the spear: cancer is a disease of the human genome and pm has been playing a critical role for decades in providing a better understanding of the disease pathology and tumors mutational profile. (1) (2) based on this knowledge, the development of diagnostics, including next-generation sequencing, equips clinicians with more precise tools to identify patients likely to benefit from targeted therapies and reduce adverse events. in addition to benefits to individuals, pm also brings efficiency in resources allocation, cost saving and cost effectiveness advantages for the healthcare systems. a study on the management of advanced non small cell lung cancer (nsclc) reveals that while pm approaches may lead to increased costs for biomarker testing and medicines in all countries, other healthcare costs are decreased, notably for the treatment of adverse events and end-of-life care (3). another analysis from a large irish private hospital revealed cost saving opportunity from reduced adverse events. with a cost of €23,718 for universal screening versus €232,061 in hospitalization expenses for side effect management, it demonstrates a significant opportunity for cost savings (4). the value of pm does not stop at individual or healthcare system level: there is an increased socio-economic value for productivity according to a study of dzau et al. (2015), which found that ph/pm innovation could generate hundreds of billions of euros in value in the form of longer, healthier lives enjoyed by patients (5). over the years, the eu commission has displayed a firm commitment to pm, with a wise mix of push and pull strategies, merging successfully bottom-up activities from member states and top-down actions from the eu institutions. with the europe's beating cancer plan (ebcp) and the eu cancer mission we have a flourishing momentum with several initiatives in precision medicine and population health, such as: uncan, to understand cancer; can.heal to unleash the power of public health genomics, diagnostics and treatment for all; pcm4eu for personalised cancer medicine for all eu citizens; and prime-rose, for a precision cancer medicine trial network. all of the above is creating a thriving innovation oncology research eco-system across europe, however, we still witness disparities in the adoption of precision medicine. disparities that negatively impact patients who “wait in average” 100 days more to access selected targeted therapies versus all oncology medicines. but for patients and us all, every day counts. we can reduce inequities in access to pm and ph innovations through smart investments and scaling up initiatives. with a push and pull strategy and a hub and spoke model, the eu could foster a world-leading cancer research environment. it could support member states to intensify and sustain investment in genome-based innovations and infrastructure with supportive policies and regulatory environment to optimize such investments. all the initiatives outside of the cancer arena (e.g., general pharmaceutical legislation, european health data space, health technology assessment regulation, in vitro diagnostics regulation) should converge – and not clash against each other’s - to materialize the vision of the eu cancer mission to save 3 million lives by 2030. there should not be contradiction with unintended consequences between all these legislative files as well as there is no contradiction between precision medicine and population health. there is a way forward for the benefit of patients and families in need, for healthcare systems, and for society. precision medicine can help face the health and wealth multi-challenges of an aging population, an increase prevalence in chronic diseases and risk of future pandemics. make it personal, for the benefit of all. make it sustainable and end the inequity (and unsustainability) of the “one size fits all” approach. don’t miss the opportunity to learn from advances in pm in cancer care which could be translated to a broader range of disease areas. (1) krzyszczyk, p., acevedo, a., davidoff, e. j., timmins, l. m., marrero-berrios, i., patel, m., white, c., lowe, c., sherba, j. j., hartmanshenn, c., o'neill, k. m., balter, m. l., fritz, z. r., androulakis, i. p., schloss, r. s., & yarmush, m. l. (2018). the growing role of precision and personalized medicine for cancer treatment. technology, 6(3-4), 79–100. https://doi.org/10.1142/s2339547818300020 50 (2) enabling precision medicine in oncology. (n.d.). retrieved october 19, 2022, from https://emea.illumina.com/destination/precision-oncology.html (3) hofmarcher, t., malmberg, c., & lindgren, p. (2023). a global analysis of the value of precision medicine in oncology – the case of non-small cell lung cancer. frontiers in medicine, 10. https://doi.org/10.3389/fmed.2023.1119506 (4) murphy, c., byrne, s., ahmed, g., kenny, a., gallagher, j., harvey, h., o'farrell, e., & bird, b. (2018). cost implications of reactive versus prospective testing for dihydropyrimidine dehydrogenase deficiency in patients with colorectal cancer: a single-institution experience. dose-response : a publication of international hormesis society, 16(4), 1559325818803042. https://doi.org/10.1177/1559325818803042 (5) dzau, v. j., ginsburg, g.s., van nuys, k., agus, d., and goldman, d. (2015). aligning incentives to fulfill the promise of personalised medicine. lancet 385(9982):2118-2119. https://doi.org/10.1016/s0140-6736(15)60722- x
millions of biospecimens curated to advance precision therapeutic and diagnostic development.
browse precision medicine news, research and analysis from the conversation
with the discipline of precision medicine as our foundation, precision medicine group leverages specialized expertise to move science closer to health.
learn about precision cancer medicine, including how precision cancer medicine is changing cancer treatment for children and
enabling breakthroughs by solving the most complex challenges in development therapeutic and diagnostic research and development.
fostering collaborative interdisciplinary research into the causes of common human disorders, such as heart disease, diabetes, obesity, and other aging-related morbidities..
traditional medicine focuses on treating disease in big groups of people. learn how precision medicine uses genes, lifestyle habits, and other things to more accurately target treatment to each person.
this illustration represents the national cancer institute’s support of research to improve precision medicine in cancer treatment, in which unique therapies treat an individual’s cancer based on specific genetic abnormalities of that person’s tumor.
explore precision medicine research and its impact, using genetics, lifestyle, and personalized treatments to create tailored healthcare strategies.
building on president obama’s announcement in his state of the union address, today the administration is unveiling details about the precision medicine initiative, a bold new rese
read how precision medicine personalizes medical treatments for individual patients, accounting for genetic, environmental and behavioral information.
nci's dictionary of cancer terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
precision medicine looks at the genetics, environment, and lifestyle of a person in order to select treatment that could work best for them.
medical forecasting is a fundamental ingredient of intelligent health. we study a full life-circle forecasting task, including the prevention, diagnosis, monitoring, and treatment. our research covers both epidemic diseases and chronic diseases. we leverage the power of machine learning and deep learning models to better predict the epidemic trends, patients’ health conditions and treatment effects […]
“precision medicine” — sometimes referred to as “individualized medicine,” “personalized medicine,” or “targeted therapy” — is, in basic terms, matching the right patients, to the right medicines, at the right time. this means gaining a deeper understanding of the specific biological, genetic, and/or molecular characteristics that are driving a patient’s tumor growth and finding or […]
learn how genetic testing can help customize your cancer treatment plan. precision medicine is improving breast cancer diagnosis, treatment and prevention.
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science has made remarkable advances in understanding the molecular basis of disease, generating new and effective rationally-designed treatments at an accelerating rate. ironically, the successes of science is creating a crisis in the affordability of equitable health care. the covid-19 pandemic underscores both the value of science in health care, and the apparently inevitable tension between health and the economy. drug development in ever-smaller target populations is a critical component of the rising costs of care. for structural and historical reasons, drug development is inefficient and poorly integrated across the public and private sectors. we postulate an alternative, integrated model in which governments and industry share the risks and benefits of drug development. the australian government recently announced support for a au$185 million innovative multi-stakeholder public-private partnership model for sustainable precision oncology, accelerating biomarker-dependent drug development through integrating clinical trials into the standard of care.
experts at nyu langone’s division of precision medicine use research results to develop new therapies and procedures for patients.
focus area: individualized therapeutics and precision medicine
articles and presentations developed by members of the cap's personalized health care committee covering a variety of precision medicine topics. examples…
learn the key differences between precision medicine versus personalized medicine and why the distinction matters in healthcare.
not just care, but not just research either. no, precision medicine requires healthcare and research to find new ways of interacting. meet the experts working at the cutting edge of healthcare. read the first article in an in-depth series about precision medicine from ki's swedish popular science magazine.
part of a multidisciplinary journal, this section explores pharmacological inhibitors that target a specific genetic defect or a particular pathway, as well as therapies targeting a specific cell p...
dinesh kotak, md, on the amazing potential precision medicine and genomics hold for preventing, diagnosing, and treating cancer.
this podcast series focuses on in-depth conversations with researchers and physicians on discoveries and emerging science in precision medicine. each episode features lively discussion between a mayo clinic colleague and guest from an external institution....
see how novartis supports education around biomarker testing and precision medicine to equip healthcare professionals to provide the best possible care.
understanding how an investment in genomics can consolidate and support a system-wide precision health strategy
learn how precision medicine leads to patient-focused care.
precision medicine is transforming healthcare by tailoring treatments to individual patients based on their unique biological makeup. this page explores the role of digital pathology in advancing precision medicine, highlighting how ai-powered image analysis and data-driven insights enhance diagnosis, research, and drug development. discover key trends, challenges, and innovations shaping the future of precision medicine, from cancer diagnostics to targeted therapies, and explore the evolving landscape of digital pathology and its impact on personalized healthcare.
offered by university of geneva. this course will provide you with the key knowledge and tools to understand the fundamentals and practical ... enroll for free.
the precision medicine initiative aims to understand how one’s genetics, environment, and lifestyle can determine the best way to prevent or treat disease.
personalized medicine and health programs can help match patients to treatments and improve survival rates, quality of life, and the cost of care.
find out how we are applying a precision medicine approach in drug development, matching the right medicine to the right patient.
genomic and precision medicine education for healthcare and businesses
precision health approaches can be used for treatment and management of diseases.
learn how msk’s expertise in precision medicine is an asset to the early drug development service.
precision or personalised medicine uses information from a person's genes alongside other health, environment and lifestyle information to determine what works best for each individual.
no more one-size-fits-all drugs. as genetic screening becomes more affordable and pharmacogenetic research diversifies, pharmacists look to implement the therapeutic benefits. by athena ponushis
precision for medicine is a clinical research organization (cro) that brings advanced technologies to help maximize insights into patient biology. contact us today.
the american medical association brings you articles and resources related to precision medicine. unlike traditional one-size-fits-all approaches, precision medicine, also referred to as "personalized medicine," customizes disease prevention and treatment to accommodate the diverse genetic, environmental and lifestyle factors of patients. the core objective of precision medicine is to provide a more precise approach for the prevention, diagnosis and treatment of disease. it harnesses the power of advanced technologies and genetic insights, to transform the way we understand and treat diseases.
precision medicine takes into account individual differences in genes, environment and lifestyle. it is a personalized medicine approach.